MAFA Polyclonal Antibody

CAT: 0866-RD253394A-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:0866-RD253394A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Members of the Maf family of basic region/leucine zipper (bZIP) transcription factors affect transcription in either a positive or negative fashion, depending on their particular protein partner and the context of the target promoter. c-Maf (Maf-2) and the closely related family members.MAFA acts as a transcriptional factor. Specifically binds the insulin enhancer element RIPE3b and activates insulin gene expression. Cooperates synergistically with NEUROD1 and PDX1. Phosphorylation by GSK3 increases its transcriptional activity and is required for its oncogenic activity.
Description
This is a MAFA Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
HMafA, Mafa, MAFA, Pancreatic beta cell specific transcriptional activator, Pancreatic beta-cell-specific transcriptional activator, RIPE3b1, Transcription factor MafA, Transcription factor RIPE3b1, v maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)
Swiss Prot
Q8NHW3
Accession Number
NP963883
Reactivity
Human, Mouse
Immunogen
Synthetic peptide of human MAFA
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, ELISA
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
1.2 mg/mL
Dilution
WB 1:500-1:2000, ELISA 1:5000-1:10000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
37 kDa
Observed Molecular Weight
Refer to figures
Host or Source
Rabbit
Isotype
IgG

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