CLK2 Polyclonal Antibody

• Background:

  This gene encodes a dual specificity protein kinase that phosphorylates serine/threonine and tyrosine-containing substrates. Activity of this protein regulates serine- and arginine-rich (SR) proteins of the spliceosomal complex, thereby influencing alternative transcript splicing. Chromosomal translocations have been characterized between this locus and the PAFAH1B3 (platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) ) gene on chromosome 19, resulting in the production of a fusion protein. Note that this gene is distinct from the TELO2 gene (GeneID:9894), which shares the CLK2 alias, but encodes a protein that is involved in telomere length regulation. There is a pseudogene for this gene on chromosome 7. Alternative splicing results in multiple transcript variants.

• Description:

  This is a CLK2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  CDC like kinase 2, CDC-like kinase 2, CLK 2, CLK kinase, CLK2, Clk2 Scamp3, CLK2, Dual specificity protein kinase CLK2, hCLK 2, hCLK2, Tu52

• Swiss Prot:

  P49760

• Accession Number:

  NP003984

• Reactivity:

  Human, Mouse

• Immunogen:

  Synthetic peptide of human CLK2

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  IHC, ELISA

• Purification Method:

  Antigen affinity purification

• Assay Type:

  Antibody

• Concentration:

  0.5 mg/mL

• Dilution:

  IHC 1:30-1:150, ELISA 1:5000-1:10000

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source:

  Rabbit

• Isotype:

  IgG