TCF7 Polyclonal Antibody

• Background:

  This gene encodes a member of the T-cell factor/lymphoid enhancer-binding factor family of high mobility group (HMG) box transcriptional activators. This gene is expressed predominantly in T-cells and plays a critical role in natural killer cell and innate lymphoid cell development. The encoded protein forms a complex with beta-catenin and activates transcription through a Wnt/beta-catenin signaling pathway. Mice with a knockout of this gene are viable and fertile, but display a block in T-lymphocyte differentiation. Alternative splicing results in multiple transcript variants. Naturally-occurring isoforms lacking the N-terminal beta-catenin interaction domain may act as dominant negative regulators of Wnt signaling.

• Description:

  This is a TCF7 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  FLJ36364, MGC47735, OTTHUMP00000159391, T cell factor 1, T cell specific transcription factor 1, T-cell factor 1, T-cell-specific transcription factor 1, TCF-1, TCF-7, TCF1, Tcf7, TCF7 transcription factor 7, TCF7, Transcription factor 7 (T cell specific HMG box), Tran

• Swiss Prot:

  P36402

• Accession Number:

  NP001128323

• Reactivity:

  Human, Mouse

• Immunogen:

  Synthetic peptide of human TCF7

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  IHC, ELISA

• Purification Method:

  Antigen affinity purification

• Assay Type:

  Antibody

• Concentration:

  0.78 mg/mL

• Dilution:

  IHC 1:40-1:200, ELISA 1:5000-1:10000

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source:

  Rabbit

• Isotype:

  IgG