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SORD Polyclonal Antibody

CAT: 0866-RD253170A-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0866-RD253170A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Sorbitol dehydrogenase (SORD; EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1; MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]) . The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD (+) cofactor.
Description
This is a SORD Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
DHSO, L iditol 2 dehydrogenase, L-iditol 2-dehydrogenase, OTTHUMP00000161939, SDH, Sorbitol dehydrogenase 1, Sorbitol dehydrogenase, SORD 1, SORD, SORD1
Swiss Prot
Q00796
Accession Number
BC021085
Reactivity
Human, Mouse
Immunogen
Fusion protein of human SORD
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
0.78 mg/mL
Dilution
IHC 1:50-1:100, ELISA 1:5000-1:10000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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