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HORMAD2 Polyclonal Antibody

CAT: 0866-RD253135A-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0866-RD253135A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Essential for synapsis surveillance during meiotic prophase via the recruitment of ATR activity. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic prophase quality control in both sexes. Required for the DNA double-strand break-independent, BRCA1-dependent activation of ATR on the sex chromosomes that is essential for normal sex body formation (By similarity) .
Description
This is a HORMAD2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
4930529M09Rik, CT46.2, HORM2, HORMA domain containing 2, HORMA domain-containing protein 2, Hormad2, MGC26710, RP23-329P17.4
Swiss Prot
Q8N7B1
Accession Number
BC030013
Reactivity
Human
Immunogen
Fusion protein of human HORMAD2
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
0.96 mg/mL
Dilution
IHC 1:50-1:100, ELISA 1:5000-1:10000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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