ARIH2 Polyclonal Antibody

• Background :

  TRIAD1, also known as ARIH2 (ariadne homolog 2) or ARI2, is a 493 amino acid protein that contains one IBR-type zinc finger and two RING-type zinc fingers and belongs to the ariadne subfamily of RBR proteins. Localized to the nucleus, TRIAD1 interacts with UBE2L3 and is thought to act as an E3 ubiquitin-protein ligase, functioning to accept ubiquitin from E2 ubiquitin-conjugating enzymes and transfer the acquired ubiquitin residue to target substrates. TRIAD1 is subject to post-translational DNA damage-dependent phosphorylation, probably by ATM or ATR. The gene encoding TRIAD1 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci.

• Description :

  This is a ARIH2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  HT005, all trans retinoic acid inducible RING finger, Ari 2, Ari-2, ARI2, ARI2, Ariadne 2, Ariadne 2 protein homolog, ariadne homolog 2 (Drosophila), ariadne homolog 2, Ariadne RBR E3 ubiquitin protein ligase 2, ARIH 2, Arih2, E3 ubiquitin protein ligase ARIH2, E3 ubiq

• Swiss Prot :

  O95376

• Accession Number :

  BC000422

• Reactivity :

  Human, Mouse

• Immunogen :

  Fusion protein of human ARIH2

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  IHC, ELISA

• Purification Method :

  Antigen affinity purification

• Assay Type :

  Antibody

• Concentration :

  1.2 mg/mL

• Dilution :

  IHC 1:50-1:300, ELISA 1:5000-1:10000

• Buffer :

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source :

  Rabbit

• Isotype :

  IgG