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RIC8A Polyclonal Antibody

CAT: 0866-RD252943A-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0866-RD252943A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G (i) -alpha protein, possibly leading to release G (i) -alpha-GTP and NuMA proteins from the NuMA-GPSM2-G (i) -alpha-GDP complex (By similarity) . Also acts as an activator for G (q) -alpha (GNAQ) protein by enhancing the G (q) -coupled receptor-mediated ERK activation.
Description
This is a RIC8A Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
MGC104517, MGC131931, MGC148073, MGC148074, Protein Ric-8A, resistance to inhibitors of cholinesterase 8 homolog A (C. elegans), RIC8, RIC8A, RIC8A, Synembryn-A
Swiss Prot
Q9NPQ8
Accession Number
BC011821
Reactivity
Human, Mouse, Rat
Immunogen
Fusion protein of human RIC8A
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
1.44 mg/mL
Dilution
IHC 1:50-1:300, ELISA 1:5000-1:10000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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