FDPS Polyclonal Antibody

• Background:

  This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.

• Description:

  This is a FDPS Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  Dimethylallyltranstransferase, Farnesyl diphosphate synthase, Farnesyl diphosphate synthetase, Farnesyl pyrophosphate synthase, Farnesyl pyrophosphate synthetase, Fdps, FPP synthase, FPP synthetase, FPPS, FPPS_HUMAN, FPS, Geranyltranstransferase

• Swiss Prot:

  P14324

• Accession Number:

  BC010004

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Fusion protein of human FDPS

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  IHC, ELISA

• Purification Method:

  Antigen affinity purification

• Assay Type:

  Antibody

• Concentration:

  1.08 mg/mL

• Dilution:

  IHC 1:50-1:300, ELISA 1:5000-1:10000

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source:

  Rabbit

• Isotype:

  IgG