ELF3 Polyclonal Antibody

• Background:

  Transcriptional activator that binds and transactivates ETS sequences containing the consensus nucleotide core sequence GGA[AT]. Acts synergistically with POU2F3 to transactivate the SPRR2A promoter and with RUNX1 to transactivate the ANGPT1 promoter. Also transactivates collagenase, CCL20, CLND7, FLG, KRT8, NOS2, PTGS2, SPRR2B, TGFBR2 and TGM3 promoters. Represses KRT4 promoter activity. Involved in mediating vascular inflammation. May play an important role in epithelial cell differentiation and tumorigenesis. May be a critical downstream effector of the ERBB2 signaling pathway. May be associated with mammary gland development and involution. Plays an important role in the regulation of transcription with TATA-less promoters in preimplantation embryos, which is essential in preimplantation development (By similarity) .

• Description:

  This is a ELF3 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  E74 like factor 3, E74 like factor 3 ets domain transcription factor, E74 like factor 3 ets domain transcription factor epithelial specific, E74 like factor 3 ETS domain transcription factor serine box epithelial specific, E74-like factor 3, Elf3, ELF3, Epitheli

• Swiss Prot:

  P78545

• Accession Number:

  BC003569

• Reactivity:

  Human

• Immunogen:

  Fusion protein of human ELF3

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  IHC, ELISA

• Purification Method:

  Antigen affinity purification

• Assay Type:

  Antibody

• Concentration:

  1.02 mg/mL

• Dilution:

  IHC 1:50-1:300, ELISA 1:5000-1:10000

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source:

  Rabbit

• Isotype:

  IgG