JPT1 Polyclonal Antibody

• Background:

  Modulates negatively AKT-mediated GSK3B signaling (PubMed:21323578, PubMed:22155408) . Induces CTNNB1 'Ser-33' phosphorylation and degradation through the suppression of the inhibitory 'Ser-9' phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions (PubMed:25169422) . Plays a role in the regulation of cell cycle and cell adhesion (PubMed:25169422, PubMed:25450365) . Has an inhibitory role on AR-signaling pathway through the induction of receptor proteosomal degradation (PubMed:22155408) .

• Description:

  This is a JPT1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  Androgen regulated protein 2, Androgen-regulated protein 2, ARM2, Hematological and neurological expressed 1, Hematological and neurological expressed 1 protein, HN1, HN1, HN1A

• Swiss Prot:

  Q9UK76

• Accession Number:

  BC001420

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Fusion protein of human JPT1

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  IHC, ELISA

• Purification Method:

  Antigen affinity purification

• Assay Type:

  Antibody

• Concentration:

  0.66 mg/mL

• Dilution:

  IHC 1:30-1:150, ELISA 1:5000-1:10000

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source:

  Rabbit

• Isotype:

  IgG