GSKIP Polyclonal Antibody

CAT: 0866-RD252808A-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:0866-RD252808A-01Size:20 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a protein that is involved as a negative regulator of GSK3-beta in the Wnt signaling pathway. The encoded protein may play a role in the retinoic acid signaling pathway by regulating the functional interactions between GSK3-beta, beta-catenin and cyclin D1, and it regulates the beta-catenin/N-cadherin pool. The encoded protein contains a GSK3-beta interacting domain (GID) in its C-terminus, which is similar to the GID of Axin. The protein also contains an evolutionarily conserved RII-binding domain, which facilitates binding with protein kinase-A and GSK3-beta, enabling its role as an A-kinase anchoring protein. Alternatively spliced transcript variants have been observed for this gene.
Description
This is a GSKIP Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
C14ORF129, Chromosome 14 open reading frame 129 , GSK3-beta interaction protein, GSK3beta interaction protein, GSKIP, GSKIP, MGC4945, UPF0279
Swiss Prot
Q9P0R6
Accession Number
BC004818
Reactivity
Human, Mouse, Rat
Immunogen
Fusion protein of human GSKIP
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
0.78 mg/mL
Dilution
IHC 1:30-1:150, ELISA 1:5000-1:10000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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