GSKIP Polyclonal Antibody

• Background :

  This gene encodes a protein that is involved as a negative regulator of GSK3-beta in the Wnt signaling pathway. The encoded protein may play a role in the retinoic acid signaling pathway by regulating the functional interactions between GSK3-beta, beta-catenin and cyclin D1, and it regulates the beta-catenin/N-cadherin pool. The encoded protein contains a GSK3-beta interacting domain (GID) in its C-terminus, which is similar to the GID of Axin. The protein also contains an evolutionarily conserved RII-binding domain, which facilitates binding with protein kinase-A and GSK3-beta, enabling its role as an A-kinase anchoring protein. Alternatively spliced transcript variants have been observed for this gene.

• Description :

  This is a GSKIP Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  C14ORF129, Chromosome 14 open reading frame 129 , GSK3-beta interaction protein, GSK3beta interaction protein, GSKIP, GSKIP, MGC4945, UPF0279

• Swiss Prot :

  Q9P0R6

• Accession Number :

  BC004818

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Fusion protein of human GSKIP

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  IHC, ELISA

• Purification Method :

  Antigen affinity purification

• Assay Type :

  Antibody

• Concentration :

  0.78 mg/mL

• Dilution :

  IHC 1:30-1:150, ELISA 1:5000-1:10000

• Buffer :

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source :

  Rabbit

• Isotype :

  IgG