Products for Research Use Only

PCSK5 Polyclonal Antibody

CAT: 0866-RD252778A-01Size: 20 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0866-RD252778A-01Size:20 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER. It then sorts to the trans-Golgi network where a second autocatalytic event takes place and the catalytic activity is acquired. This encoded protein is widely expressed and one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. It mediates posttranslational endoproteolytic processing for several integrin alpha subunits and is thought to process prorenin, pro-membrane type-1 matrix metalloproteinase and HIV-1 glycoprotein gp160. Alternative splicing results in multiple transcript variants, some of which encode distinct isoforms, including a protease packaged into dense core granules (PC5A) and a type 1 membrane bound protease (PC5B) .
Description
This is a PCSK5 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
FLJ11149, FLJ16215, hPC6, PC5, PC6, PC6A, Pcsk5, PCSK5, Prohormone convertase 5, Proprotein convertase 5, Proprotein convertase 6, Proprotein convertase PC5, Proprotein convertase subtilisin/kexin type 5, Protease PC6, SPC6, Subtilisin/kexin-like protease PC5
Swiss Prot
Q92824
Accession Number
BC012064
Reactivity
Human, Mouse, Rat
Immunogen
Fusion protein of human PCSK5
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
0.84 mg/mL
Dilution
IHC 1:25-1:100, ELISA 1:5000-1:10000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG