QDPR Polyclonal Antibody

• Background:

  This gene encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems. Mutations in this gene resulting in QDPR deficiency include aberrant splicing, amino acid substitutions, insertions, or premature terminations. Dihydropteridine reductase deficiency presents as atypical phenylketonuria due to insufficient production of biopterin, a cofactor for phenylalanine hydroxylase.

• Description:

  This is a QDPR Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  6,7 dihydropteridine reductase, DHPR, DHPR, Dihydropteridine reductase, HDHPR, HPR, PKU2, Qdpr, Quinoid dihydropteridine reductase, SDR33C1, Short chain dehydrogenase/reductase family 33C, member 1

• Swiss Prot:

  P09417

• Accession Number:

  BC000576

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Fusion protein of human QDPR

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IHC, ELISA

• Purification Method:

  Antigen affinity purification

• Assay Type:

  Antibody

• Concentration:

  1.2 mg/mL

• Dilution:

  WB 1:500-1:2000, IHC 1:50-1:200, ELISA 1:5000-1:10000

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  26 kDa

• Observed Molecular Weight:

  Refer to figures

• Host or Source:

  Rabbit

• Isotype:

  IgG