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IGHA1 Polyclonal Antibody

CAT: 0866-RD252649A-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0866-RD252649A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268) . The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V- (D) -J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268) . Ig alpha is the major immunoglobulin class in body secretions (PubMed:2241915) .
Description
This is a IGHA1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
FLJ14473, FLJ35065, FLJ35500, FLJ36402, FLJ39698, FLJ40001, FLJ41548, FLJ41552, FLJ41789, FLJ43248, FLJ43594, FLJ44293, FLJ46028, FLJ46621, FLJ46724, FLJ46811, FLJ46824, FLJ90170, Ig alpha 1 chain C region, IgA1, IGHA1, immunoglobulin heavy constant alpha 1, MGC102857
Swiss Prot
P01876
Accession Number
BC005951
Reactivity
Human
Immunogen
Fusion protein of human IGHA1
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
0.9 mg/mL
Dilution
IHC 1:50-1:300, ELISA 1:5000-1:10000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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