VASP Polyclonal Antibody

• Background:

  Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG.

• Description:

  This is a VASP Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  Vasodilator stimulated phosphoprotein, Vasodilator-stimulated phosphoprotein, VASP, VASP

• Swiss Prot:

  P50552

• Accession Number:

  BC038224

• Reactivity:

  Human, Mouse

• Immunogen:

  Fusion protein of human VASP

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IHC, ELISA

• Purification Method:

  Antigen affinity purification

• Assay Type:

  Antibody

• Concentration:

  0.5 mg/mL

• Dilution:

  WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  40 kDa

• Observed Molecular Weight:

  Refer to figures

• Host or Source:

  Rabbit

• Isotype:

  IgG