EDARADD Polyclonal Antibody

• Background:

  This gene was identified by its association with ectodermal dysplasia, a genetic disorder characterized by defective development of hair, teeth, and eccrine sweat glands. The protein encoded by this gene is a death domain-containing protein, and is found to interact with EDAR, a death domain receptor known to be required for the development of hair, teeth and other ectodermal derivatives. This protein and EDAR are coexpressed in epithelial cells during the formation of hair follicles and teeth. Through its interaction with EDAR, this protein acts as an adaptor, and links the receptor to downstream signaling pathways. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

• Description:

  This is a EDARADD Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  Cr, Crinkled homolog, ectodysplasia A receptor associated death domain, Ectodysplasin-A receptor-associated adapter protein, ED3, EDA3, EDAD, EDAR associated death domain, EDAR-associated death domain protein, EDARADD, Protein crinkled homolog

• Swiss Prot:

  Q8WWZ3

• Accession Number:

  BC128082

• Reactivity:

  Human

• Immunogen:

  Full length fusion protein

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  IHC, ELISA

• Purification Method:

  Antigen affinity purification

• Assay Type:

  Antibody

• Concentration:

  0.9 mg/mL

• Dilution:

  IHC 1:35-1:200, ELISA 1:5000-1:10000

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source:

  Rabbit

• Isotype:

  IgG