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FNDC3B Polyclonal Antibody

CAT: 0866-RD252260A-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0866-RD252260A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Adipogenesis, the process of transforming pre-adipocytes into mature fat cells, is of particular interest due to the role adipocytes play in obesity and type II diabetes. Adipocytes have been shown to affect a variety of functions, including hemostasis, angiogenesis and energy balance, by secreting hormones and bioactive peptides. The FNDC3B protein, also designated FAD104 (factor for adipocyte differentiation 104) or HCV NS5A-binding protein 37, is expressed during early adipogenesis. Belonging to the FNDC3 family of proteins, FNDC3B is a 1,204 amino acid protein that contains nine fibronectin type-III domains. FNDC3B-deficient mice die within one day of birth, suggesting that FNDC3B is crucial for postpartum survival. Mouse embryonic fibroblasts (MEFs) with loss of FNDC3B function displayed a reduction in stress fiber formation, indicating a role for FNDC3B in cell proliferation, adhesion, spreading and migration.
Description
This is a FNDC3B Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
DKFZp686D14170 , DKFZp762K137, Factor for adipocyte differentiation 104, FAD104, fibronectin type III domain containing 3B , FLJ23399, HCV NS5A binding protein 37 , MGC10002, NS5ABP37, PRO4979, YVTM2421
Swiss Prot
Q53EP0
Accession Number
BC012204
Reactivity
Human, Mouse
Immunogen
Full length fusion protein
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
1.8 mg/mL
Dilution
IHC 1:30-1:150, ELISA 1:5000-1:10000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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