KCNN2 Polyclonal Antibody

CAT: 0866-RD252083A-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:0866-RD252083A-01Size:20 µL
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Background
Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. This gene is a member of the KCNN family of potassium channel genes. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. Alternate splicing of this gene results in multiple transcript variants. KCNN2 (Potassium Calcium-Activated Channel Subfamily N Member 2) is a Protein Coding gene. Among its related pathways are Serotonergic synapse and Bile secretion. GO annotations related to this gene include protein homodimerization activity and ion channel activity. An important paralog of this gene is KCNN3.
Description
This is a KCNN2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
Apamin sensitive small conductance Ca2+ activated potassium, Apamin sensitive small conductance Ca2+ activated potassium channel, hSK2, KCa2.2, Kcnn2, Potassium intermediate/small conductance calcium activated, Potassium intermediate/small conductance calcium a
Swiss Prot
Q9H2S1
Accession Number
NP067627
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide of human KCNN2
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
0.78 mg/mL
Dilution
IHC 1:30-1:150, ELISA 1:5000-1:10000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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