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ZBTB33 Polyclonal Antibody

CAT: 0866-RD252062A-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0866-RD252062A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a transcriptional regulator with bimodal DNA-binding specificity, which binds to methylated CGCG and also to the non-methylated consensus KAISO-binding site TCCTGCNA. The protein contains an N-terminal POZ/BTB domain and 3 C-terminal zinc finger motifs. It recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. It may contribute to the repression of target genes of the Wnt signaling pathway, and may also activate transcription of a subset of target genes by the recruitment of catenin delta-2 (CTNND2) . Its interaction with catenin delta-1 (CTNND1) inhibits binding to both methylated and non-methylated DNA. It also interacts directly with the nuclear import receptor Importin-α2 (also known as karyopherin alpha2 or RAG cohort 1), which may mediate nuclear import of this protein. Alternatively spliced transcript variants encoding the same protein have been identified.
Description
This is a ZBTB33 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
Kaiso, Kaiso protein, Kaiso transcription factor, KAISO, Transcriptional regulator Kaiso, ZBTB 33, Zbtb33, Zinc finger and BTB domain containing 33, Zinc finger and BTB domain-containing protein 33, Zinc finger transcription factor Kaiso, ZNF 348, ZNF Kaiso, ZNF348
Swiss Prot
Q86T24
Accession Number
NP006768
Reactivity
Human
Immunogen
Synthetic peptide of human ZBTB33
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
0.9 mg/mL
Dilution
IHC 1:40-1:200, ELISA 1:5000-1:10000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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