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JAM3 Polyclonal Antibody

CAT: 0866-RD252059A-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:0866-RD252059A-01Size:20 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. Unlike other proteins in this family, the this protein is unable to adhere to leukocyte cell lines and only forms weak homotypic interactions. The encoded protein is a member of the junctional adhesion molecule protein family and acts as a receptor for another member of this family. A mutation in an intron of this gene is associated with hemorrhagic destruction of the brain, subependymal calcification, and congenital cataracts. Alternative splicing results in multiple transcript variants.
Description
This is a JAM3 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
FLJ14529, JAM 2 , JAM 3, JAM C, JAM-2, JAM-3, JAM-C, JAM2 , Jam3, JAM3, JAMC, Junctional adhesion molecule 3, Junctional adhesion molecule 3 precursor, Junctional adhesion molecule C
Swiss Prot
Q9BX67
Accession Number
NP116190
Reactivity
Human, Mouse
Immunogen
Synthetic peptide of human JAM3
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, ELISA
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
1.32 mg/mL
Dilution
WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
35 kDa
Observed Molecular Weight
Refer to figures
Host or Source
Rabbit
Isotype
IgG

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