JAM3 Polyclonal Antibody

• Background:

  Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. Unlike other proteins in this family, the this protein is unable to adhere to leukocyte cell lines and only forms weak homotypic interactions. The encoded protein is a member of the junctional adhesion molecule protein family and acts as a receptor for another member of this family. A mutation in an intron of this gene is associated with hemorrhagic destruction of the brain, subependymal calcification, and congenital cataracts. Alternative splicing results in multiple transcript variants.

• Description:

  This is a JAM3 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  FLJ14529, JAM 2 , JAM 3, JAM C, JAM-2, JAM-3, JAM-C, JAM2 , Jam3, JAM3, JAMC, Junctional adhesion molecule 3, Junctional adhesion molecule 3 precursor, Junctional adhesion molecule C

• Swiss Prot:

  Q9BX67

• Accession Number:

  NP116190

• Reactivity:

  Human, Mouse

• Immunogen:

  Synthetic peptide of human JAM3

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IHC, ELISA

• Purification Method:

  Antigen affinity purification

• Assay Type:

  Antibody

• Concentration:

  1.32 mg/mL

• Dilution:

  WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  35 kDa

• Observed Molecular Weight:

  Refer to figures

• Host or Source:

  Rabbit

• Isotype:

  IgG