ITPR2 Polyclonal Antibody

CAT: 0866-RD252051A-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:0866-RD252051A-01Size:20 µL
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Background
Inositol 1,4,5-triphosphate (IP3) functions as a second messenger for a myriad of extracellular stimuli including hormones, growth factors and neurotransmitters. Receptor tyrosine kinases indirectly increase the intracellular levels of IP3 through the activation of phospholipases such as phospholipase C (PLC), which convert phosphatidylinositol-4,5 bisphosphate into IP3 and diacylglycerol (DAG) . The inositol 1,4,5-triphosphate receptor, IP3R, acts as an inositol triphosphate (IP3) -gated calcium release channel in a variety of cell types. Three IP3 receptor subtypes have been described and are designated IP3R-I, IP3R-II and IP3R-III. IP3R-I is the predominant IP3R subtype expressed in neuronal tissues and the central nervous system, but is also expressed at high levels in the liver.
Description
This is a ITPR2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
4,5-trisphosphate receptor, Inositol 1 4 5 trisphosphate receptor type 2, Inositol 1,4,5-trisphosphate receptor type 2, Inositol 145 trisphosphate receptor type 2, InsP3 R2, InsP3R2, IP3 R2, IP3 receptor, IP3 receptor isoform 2, IP3R 2, IP3R2, ITPR 2, Itpr2, ITPR2, Typ
Swiss Prot
Q14571
Accession Number
NP002214
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide of human ITPR2
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
1.74 mg/mL
Dilution
IHC 1:50-1:300, ELISA 1:5000-1:10000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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