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Angiotensinogen Polyclonal Antibody

CAT: 0866-RD240478A-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0866-RD240478A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Angiotensinogen is a precursor of angiotensin II (Ang II), is expressed and synthesized largely in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. It has a key role in mediating vascular constriction and regulating salt and fluid homeostasis. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.
Description
This is a Angiotensinogen Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
Aangiotensinogen (serpin peptidase inhibitor clade A member 8), AGT, AI265500, Alpha 1 antiproteinase antitrypsin, Ang, Ang I, Ang II, Ang III, AngII, Angiotensin I, Angiotensin II, Angiotensin III, Angiotensin-3, Angiotensinogen (PAT), Angiotensinogen, A
Gene ID
183
Swiss Prot
P11859
Reactivity
Mouse, Rat
Immunogen
Recombinant Mouse Angiotensinogen protein
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
WB, IHC
Purification Method
Antigen Affinity Purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:2000-1:5000 IHC 1:100-1:300
Buffer
PBS with 0.05% Proclin300, 50% glycerol, pH7.3.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
52 kDa
Observed Molecular Weight
52 kDa
Host or Source
Rabbit
Isotype
IgG

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