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HRAS Polyclonal Antibody

CAT: 0866-RD240406A-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0866-RD240406A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene.
Description
This is a HRAS Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
C BAS/HAS, C HA RAS1, CTLO, H Ras 1, H RASIDX, HAMSV, HRAS1, Harvey rat sarcoma viral oncogene homolog, K ras, N ras, p19 H RasIDX protein, p21ras, RASH1, Transforming protein p21, vHa RAS
Gene ID
3265
Swiss Prot
P01112
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant Human GTPase HRas protein
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC
Purification Method
Antigen Affinity Purification
Assay Type
Antibody
Concentration
0.78 mg/mL
Dilution
IHC 1:100-1:300
Buffer
PBS with 0.05% Proclin300, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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