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PLAUR Polyclonal Antibody

CAT: 0866-RD240370A-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0866-RD240370A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined.
Description
This is a PLAUR Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
CD 87, CD87, CD87 antigen, MO 3, MO3, Monocyte activation antigen Mo3, Plasminogen activator receptor urokinase, Plasminogen activator urokinase receptor, PLAUR, U PAR, u plasminogen activator receptor, U-PAR, u-plasminogen activator receptor form 2, UPA receptor, uPAR
Gene ID
5329
Swiss Prot
Q03405
Reactivity
Human, Mouse
Immunogen
Recombinant Human Urokinase plasminogen activator surface receptor protein
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC
Purification Method
Antigen Affinity Purification
Assay Type
Antibody
Concentration
0.85 mg/mL
Dilution
IHC 1:100-1:300
Buffer
PBS with 0.05% Proclin300, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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