PLAUR Polyclonal Antibody

• Background :

  This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined.

• Description :

  This is a PLAUR Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  CD 87, CD87, CD87 antigen, MO 3, MO3, Monocyte activation antigen Mo3, Plasminogen activator receptor urokinase, Plasminogen activator urokinase receptor, PLAUR, U PAR, u plasminogen activator receptor, U-PAR, u-plasminogen activator receptor form 2, UPA receptor, uPAR

• Gene ID :

  5329

• Swiss Prot :

  Q03405

• Reactivity :

  Human, Mouse

• Immunogen :

  Recombinant Human Urokinase plasminogen activator surface receptor protein

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  IHC

• Purification Method :

  Antigen Affinity Purification

• Assay Type :

  Antibody

• Concentration :

  0.85 mg/mL

• Dilution :

  IHC 1:100-1:300

• Buffer :

  PBS with 0.05% Proclin300, 50% glycerol, pH7.3

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source :

  Rabbit

• Isotype :

  IgG