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Aβ40 Polyclonal Antibody

CAT: 0866-RD240070A-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0866-RD240070A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Aβ derives from APP via proteolytic cleavage by proteases called α-, β- and γ-secretase. The α-secretase cleavage precludes the formation of Aβ, while the β- and γ-cleavages generate APP components with amyloidogenic features. Amyloid beta A4 precursor protein (APP), encoded by APP gene which locate on human chromosome 21q, is a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. APP expressed in all fetal tissues and is pronounced in brain, kidney, heart and spleen, but weak in liver. Defects in APP are the cause of Alzheimer disease type 1 (AD1) . This antibody can recogniaze the N-terminus of human APP: Soluble APP-alpha and Soluble APP-beta.
Description
This is a Aβ40 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
A4 amyloid protein, A4, AAA, ABETA, ABPP, AD1, AICD-50, AICD-57, AICD-59, AID (50), AID (57), AID (59), Alzheimer disease amyloid protein, Amyloid beta (A4) precursor protein, Amyloid beta A4 protein, Amyloid beta protein, Amyloid intracellular domain 50, Amyloid intracellul
Swiss Prot
P05067
Reactivity
Mouse, Rat
Immunogen
Recombinant Human Beta-amyloid 40 protein
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
2 mg/mL
Dilution
IHC 1:50-1:100
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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