SNCA Polyclonal Antibody

• Background:

  Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene.

• Description:

  This is a SNCA Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  Alpha synuclein, Alpha-synuclein, Alpha-synuclein, isoform NACP140, alphaSYN, MGC105443, MGC110988, MGC127560, MGC64356, NACP, Non A beta component of AD amyloid, Non A4 component of amyloid, Non A4 component of amyloid precursor, Non-A beta component of AD amyloid, No

• Swiss Prot:

  P37840

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Synthesized peptide derived from the Internal region of human Synuclein-α.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IHC-p, ELISA

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000, IHC 1:100-1:300 ELISA 1:10000

• Buffer:

  PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol pH 7.4.

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  14 kDa

• Observed Molecular Weight:

  15 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG