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RYR2 Polyclonal Antibody

CAT: 0866-RD232840A-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0866-RD232840A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a ryanodine receptor found in cardiac muscle sarcoplasmic reticulum. The encoded protein is one of the components of a calcium channel, composed of a tetramer of the ryanodine receptor proteins and a tetramer of FK506 binding protein 1B proteins, that supplies calcium to cardiac muscle. Mutations in this gene are associated with stress-induced polymorphic ventricular tachycardia and arrhythmogenic right ventricular dysplasia.RYR2 (Ryanodine Receptor 2) is a Protein Coding gene. Diseases associated with RYR2 include Ventricular Tachycardia, Catecholaminergic Polymorphic, 1 and Arrhythmogenic Right Ventricular Dysplasia 2. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Cell-type Dependent Selectivity of CCK2R Signaling. GO annotations related to this gene include calcium ion binding and protein kinase binding. An important paralog of this gene is RYR3.
Description
This is a RYR2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
ARVC2, ARVD2, Cardiac muscle ryanodine receptor, Cardiac muscle ryanodine receptor-calcium release channel, hRYR-2, ryanodine receptor 2 (cardiac), Ryanodine receptor 2, RyR, RYR-2, RyR2, RYR2, Type 2 ryanodine receptor, VTSIP
Swiss Prot
Q92736
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from human RyR-2 around the non-phosphorylation site of Ser2808.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC-p, IF, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:5000
Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
564 kDa
Observed Molecular Weight
200-300 kDa
Host or Source
Rabbit
Isotype
IgG

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