Products for Research Use Only

RUNX2 Polyclonal Antibody

CAT: 0866-RD230103A-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0866-RD230103A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Transcription factor involved in osteoblastic differentiation and skeletal morphogenesis. Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, osteocalcin, osteopontin, bone sialoprotein, alpha 1 (I) collagen, LCK, IL-3 and GM-CSF promoters (By similarity) . Inhibits MYST4-dependent transcriptional activation.
Description
This is a RUNX2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
Acute myeloid leukemia 3 protein, Alpha subunit 1, AML3, CBF alpha 1, CBF-alpha-1, CBFA1, CCD, CCD1, Cleidocranial dysplasia 1, Core binding factor, Core binding factor runt domain alpha subunit 1, Core binding factor subunit alpha 1, Core-binding factor subunit alph
Swiss Prot
Q13950
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the Internal region of human RUNX2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IF, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000, IF 1:50-1:200, ELISA 1:20000
Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
57 kDa
Observed Molecular Weight
56 kDa
Host or Source
Rabbit
Isotype
IgG