RGR Polyclonal Antibody

• Background :

  This gene encodes a putative retinal G-protein coupled receptor. The gene is a member of the opsin subfamily of the 7 transmembrane, G-protein coupled receptor 1 family. Like other opsins which bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. The protein acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal. The reverse isomerization occurs with rhodopsin in retinal photoreceptor cells. The protein is exclusively expressed in tissue adjacent to retinal photoreceptor cells, the retinal pigment epithelium and Mueller cells. This gene may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP, respectively) . Alternative splicing results in multiple transcript variants encoding different isoforms.

• Description :

  This is a RGR Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  HRGR, Ral GDS related protein, Retinal G protein coupled receptor, RGR-opsin, RP44, RPE retinal G protein coupled receptor

• Swiss Prot :

  P47804

• Accession Number :

  NP001012738

• Reactivity :

  Human, Mouse

• Immunogen :

  Synthetic peptide of human RGR

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  WB, IHC, ELISA

• Purification Method :

  Antigen affinity purification

• Assay Type :

  Antibody

• Concentration :

  0.78 mg/mL

• Dilution :

  WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000

• Buffer :

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  32 kDa

• Observed Molecular Weight :

  Refer to figures

• Host or Source :

  Rabbit

• Isotype :

  IgG