GPT2 Polyclonal Antibody

• Background:

  This gene encodes a mitochondrial alanine transaminase, a pyridoxal enzyme that catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate. Alanine transaminases play roles in gluconeogenesis and amino acid metabolism in many tissues including skeletal muscle, kidney, and liver. Activating transcription factor 4 upregulates this gene under metabolic stress conditions in hepatocyte cell lines. A loss of function mutation in this gene has been associated with developmental encephalopathy. Alternative splicing results in multiple transcript variants.

• Synonyms:

  AAT2,Alanine aminotransferase 2,ALAT2,ALT2,Glutamate pyruvate transaminase 2,Glutamic alanine transaminase 2,Glutamic pyruvate transaminase (alanine aminotransferase) 2,Glutamic pyruvic transaminase 2,Glutamic--alanine transaminase 2,Glutamic--pyruvic transaminase 2,GPT 2,gpt2

• Swiss Prot:

  Q8TD30

• Accession Number:

  NP597700

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Synthetic peptide of human GPT2

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Conjugation:

  Unconjugated

• Applications:

  IHC,ELISA

• Purification:

  Antigen affinity purification

• Concentration:

  2.16 mg/mL

• Dilution:

  IHC 1:25-1:100, ELISA 1:5000-1:10000

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• CAS Number:

  9007-83-4