ACOD1 Polyclonal Antibody

• Background :

  Involved in the inhibition of the inflammatory response. Acts as a negative regulator of the Toll-like receptors (TLRs) -mediated inflammatory innate response by stimulating the tumor necrosis factor alpha-induced protein TNFAIP3 expression via reactive oxygen species (ROS) in LPS-tolerized macrophages. Involved in antimicrobial response of innate immune cells; ACOD1-mediated itaconic acid production contributes to the antimicrobial activity of macrophages. Plays a role in the embryo implantation.

• Description :

  This is a ACOD1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  ACOD1, Aconitate decarboxylase 1, Aconitate decarboxylase, CAD, Cis aconitate decarboxylase, Immune responsive gene 1 protein homolog, Immune-responsive gene 1 protein homolog, Immunoresponsive 1 homolog (mouse), Irg1, IRG1, OC116, OPTB1, TCTIRC7

• Swiss Prot :

  A6NK06

• Accession Number :

  NP001245335

• Reactivity :

  Human, Mouse

• Immunogen :

  Synthetic peptide of human ACOD1

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  WB, ELISA

• Purification Method :

  Antigen affinity purification

• Assay Type :

  Antibody

• Concentration :

  1.32 mg/mL

• Dilution :

  WB 1:500-1:2000, ELISA 1:5000-1:10000

• Buffer :

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  53 kDa

• Observed Molecular Weight :

  Refer to figures

• Host or Source :

  Rabbit

• Isotype :

  IgG