MECOM Polyclonal Antibody

• Background:

  The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene.

• Description:

  This is a MECOM Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  Ecotropic Virus Integration Site 1 Protein Homolog, MDS1 And EVI1 Complex Locus Protein, PR Domain 3, EVI1, MDS1, MDS1 And EVI1 Complex Locus Protein EVI1, MDS1 And EVI1 Complex Locus Protein MDS1, Ecotropic Viral Integration Site 1, Myelodysplasia Syndrome 1 Pro

• Swiss Prot:

  Q03112

• Accession Number:

  NP005232

• Reactivity:

  Human, Mouse

• Immunogen:

  Synthetic peptide of human MECOM

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  IHC, ELISA

• Purification Method:

  Antigen affinity purification

• Assay Type:

  Antibody

• Concentration:

  1.68 mg/mL

• Dilution:

  IHC 1:40-1:200, ELISA 1:5000-1:10000

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source:

  Rabbit

• Isotype:

  IgG