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KLF1 Polyclonal Antibody

CAT: 0866-RD219799A-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0866-RD219799A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In (Lu) blood phenotype.KLF1 (Kruppel Like Factor 1) is a Protein Coding gene. Diseases associated with KLF1 include Dyserythropoietic Anemia, Congenital, Type Iv and Hereditary Persistence Of Fetal Hemoglobin-Sickle Cell Disease Syndrome. Among its related pathways are Hematopoietic Stem Cell Differentiation. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and core promoter proximal region sequence-specific DNA binding. An important paralog of this gene is KLF4.
Description
This is a KLF1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
CDAN4, EKLF, EKLF PEN, Erythroid krueppel like transcription factor (EKLF) (Erythroid transcription factor), Erythroid krueppel-like transcription factor, Erythroid Kruppel like factor, Erythroid specific transcription factor EKLF, HBFQTL6, Human erythroid-specif
Swiss Prot
Q13351
Accession Number
NP006554
Reactivity
Human
Immunogen
Synthetic peptide of human KLF1
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
0.96 mg/mL
Dilution
IHC 1:50-1:100, ELISA 1:2000-1:5000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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