HIST1H2BA Polyclonal Antibody

• Background:

  The nucleosome, made up of four core histone proteins (H2A, H2B, H3, and H4), is the primary building block of chromatin. Originally thought to function as a static scaffold for DNA packaging, histones have now been shown to be dynamic proteins, undergoing multiple types of post-translational modifications, including acetylation, phosphorylation, methylation, and ubiquitination , acetylation of specific lysine residues creates docking sites that facilitate recruitment of many transcription and chromatin regulatory proteins that contain a bromodomain, which binds to acetylated lysine residues . Histone H2B is rapidly phosphorylated at irradiation-induced DNA damage foci in mouse embryonic fibroblasts .

• Description:

  This is a HIST1H2BA Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  HIST1H2BA, testis, bA317E16.3, H2B, H2B histone family member U, H2B histone family member U testis specific, H2B histone family, member U, (testis specific), H2B testis, H2B1A, H2BFU, H2BT, HIST1H2BA, Histone 1, H2ba, Histone cluster 1 H2ba, Histone H2B, Histone H2B testi

• Swiss Prot:

  Q96A08

• Accession Number:

  NP733759

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Synthetic peptide of human HIST1H2BA

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IHC, ELISA

• Purification Method:

  Antigen affinity purification

• Assay Type:

  Antibody

• Concentration:

  1.98 mg/mL

• Dilution:

  WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  14 kDa

• Observed Molecular Weight:

  Refer to figures

• Host or Source:

  Rabbit

• Isotype:

  IgG