MORF4L2 Polyclonal Antibody

CAT: 0866-RD219745A-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:0866-RD219745A-01Size:20 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the MSIN3A complex which acts to repress transcription by deacetylation of nucleosomal histones.
Description
This is a MORF4L2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
KIAA0026 , MO4L2, MORF related gene X protein, MORF-related gene X protein, Morf4l2, MORFL2, Mortality factor 4 like protein 2, Mortality factor 4-like protein 2, MRGX, MSL3 2 protein, Protein MSL3-2, Transcription factor like protein MRGX , Transcription factor-like
Swiss Prot
Q15014
Accession Number
NP036418
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide of human MORF4L2
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, ELISA
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
0.7 mg/mL
Dilution
WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
32 kDa
Observed Molecular Weight
Refer to figures
Host or Source
Rabbit
Isotype
IgG

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