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ZNHIT3 Polyclonal Antibody

CAT: 0866-RD219558A-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0866-RD219558A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
ZNHIT3 (zinc finger, HIT-type containing 3), also known as TRIP3 (thyroid receptor-interacting protein 3) or HNF-4a coactivator, is a 155 amino acid protein that contains one HIT-type zinc finger and regulates PPAR-mediated adipocyte differentiation. ZNHIT3 also coactivates HNF-4, and as a thyroid receptor interacting protein, ZNHIT3 interacts with the ligand binding domain of the thyroid receptor. The gene encoding ZNHIT3 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.
Description
This is a ZNHIT3 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
HNF 4a coactivator , Thyroid hormone receptor interactor 3, Thyroid receptor interacting protein 3, TR interacting protein 3, TRIP 3, TRIP3, Zinc finger HIT domain containing protein 3, Zinc finger HIT type 3, Zinc finger, HIT domain containing 3, Zinc finger, HIT
Swiss Prot
Q15649
Accession Number
NP004764
Reactivity
Human
Immunogen
Synthetic peptide of human ZNHIT3
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
1.9 mg/mL
Dilution
IHC 1:40-1:250, ELISA 1:5000-1:10000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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