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HUWE1 Polyclonal Antibody

CAT: 0866-RD219540A-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0866-RD219540A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a protein containing a C-terminal HECT (E6AP type E3 ubiquitin protein ligase) domain that functions as an E3 ubiquitin ligase. The encoded protein is required for the ubiquitination and subsequent degradation of the anti-apoptotic protein Mcl1 (myeloid cell leukemia sequence 1 (BCL2-related) ) . This protein also ubiquitinates the p53 tumor suppressor, core histones, and DNA polymerase beta. Mutations in this gene are associated with Turner type X-linked syndromic mental retardation.
Description
This is a HUWE1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
ARF binding protein 1, ARF BP1, ARF-binding protein 1, ARF-BP1, BJ-HCC-24 tumor antigen, E3 ubiquitin protein ligase HUWE1, E3 ubiquitin-protein ligase HUWE1, HECT, HECT domain protein LASU1, HECT UBA and WWE domain containing protein 1, HectH9, Homologous to E6AP c
Swiss Prot
Q7Z6Z7
Accession Number
NP113584
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide of human HUWE1
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
0.8 mg/mL
Dilution
IHC 1:10-1:50, ELISA 1:5000-1:10000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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