IBSP Polyclonal Antibody

• Background:

  The protein encoded by this gene is a major structural protein of the bone matrix. It constitutes approximately 12% of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor.

• Description:

  This is a IBSP Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  BNSP, Bone sialoprotein 2, Bone sialoprotein II, BSP, BSP II, BSPII, Cell binding sialoprotein, Cell-binding sialoprotein, IBSP, Integrin binding sialoprotein, Integrin-binding sialoprotein, SIAL, SPII

• Swiss Prot:

  P21815

• Accession Number:

  NP004958

• Reactivity:

  Human, Mouse

• Immunogen:

  Synthetic peptide of human IBSP

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IHC, ELISA

• Purification Method:

  Antigen affinity purification

• Assay Type:

  Antibody

• Concentration:

  0.84 mg/mL

• Dilution:

  WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  35 kDa

• Observed Molecular Weight:

  Refer to figures

• Host or Source:

  Rabbit

• Isotype:

  IgG