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PAX5 Polyclonal Antibody

CAT: 0866-RD219303A-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0866-RD219303A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
PAX5, also named B-cell specific activator protein (BSAP), is a member of the highly conserved paired box (PAX) -domain family of transcription factors. PAX5 is essential in normal B-cell lymphopoiesis. It is expressed in pro-B, pre-B and mature B lymphocytes but not in plasma cells. PAX5 is a common target in leukemogenesis of B-ALL (B-lineage acute lymphoblastic leukemia) along with CDKN2A. Owing to its frequent deletion in B-ALL, PAX5 could be used as one of the molecular markers in diagnosis and monitoring of the disease. This antibody is specific to PAX5. It will not cross react with other PAX members.
Description
This is a PAX5 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
B cell lineage specific activator, B cell lineage specific activator protein, B cell specific activator protein, B cell specific transcription factor, B-cell-specific transcription factor, BSAP, EBB-1, KLP, Paired box 5, Paired box gene 5 (B cell lineage specific
Swiss Prot
Q02548
Accession Number
NP057953
Reactivity
Human, Mouse
Immunogen
Synthetic peptide of human PAX5
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
0.84 mg/mL
Dilution
IHC 1:30-1:150, ELISA 1:5000-1:10000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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