PSMA6 Polyclonal Antibody

• Background:

  The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Multiple transcript variants encoding several different isoforms have been found for this gene. A pseudogene has been identified on the Y chromosome.

• Description:

  This is a PSMA6 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  27 kDa prosomal protein, IOTA, Macropain iota chain, Macropain subunit iota, MGC22756, MGC2333, MGC23846, Multicatalytic endopeptidase complex iota chain, p27K, PROS 27, PROS-27, PROS27, Prosomal P27K protein, Proteasome (prosome macropain) subunit alpha type 6, Protea

• Swiss Prot:

  P60900

• Accession Number:

  BC002979

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Fusion protein of human PSMA6

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IHC, ELISA

• Purification Method:

  Antigen affinity purification

• Assay Type:

  Antibody

• Concentration:

  1.56 mg/mL

• Dilution:

  WB 1:1000-1:5000, IHC 1:100-1:300, ELISA 1:5000-1:10000

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  27 kDa

• Observed Molecular Weight:

  Refer to figures

• Host or Source:

  Rabbit

• Isotype:

  IgG