DNAJA4 Polyclonal Antibody

• Background:

  The DnaJ family is one of the largest of all the chaperone families and has evolved with diverse cellular localization and functions. The presence of the J domain defines a protein as a member of the DnaJ family. DnaJ heat shock induced proteins are from the bacterium Escherichia coli and are under the control of the htpR regulatory protein. The DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP hydrolysis. The proteins contain cysteine rich regions that are composed of zinc fingers that form a peptide binding domain responsible for the chaperone function. DnaJ proteins are important mediators of proteolysis and are involved in the regulation of protein degradation, exocytosis and endocytosis. DnaJA4 (DnaJ homolog subfamily A member 4) is a SREBP-regulated chaperone that is thought to regulate the cholesterol biosynthesis pathway.

• Description:

  This is a DNAJA4 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  DnaJ (Hsp40) homolog subfamily A member 4, DnaJ (Hsp40) homolog, subfamily A, member4, DNAJ A4, DnaJ heat shock protein family (Hsp40) member A4, DnaJ homolog subfamily A member 4, DNAJA 4, DNAJA4, DNJA4, MST104, MSTP104, PRO1472

• Swiss Prot:

  Q8WW22

• Accession Number:

  BC031044

• Reactivity:

  Human, Mouse

• Immunogen:

  Fusion protein of human DNAJA4

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IHC, ELISA

• Purification Method:

  Antigen affinity purification

• Assay Type:

  Antibody

• Concentration:

  0.96 mg/mL

• Dilution:

  WB 1:500-1:2000, IHC 1:50-1:200, ELISA 1:5000-1:10000

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  45 kDa

• Observed Molecular Weight:

  Refer to figures

• Host or Source:

  Rabbit

• Isotype:

  IgG