POLH Polyclonal Antibody

• Background :

  This gene encodes a member of the Y family of specialized DNA polymerases. It copies undamaged DNA with a lower fidelity than other DNA-directed polymerases. However, it accurately replicates UV-damaged DNA; when thymine dimers are present, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV-induced DNA damage. This polymerase is thought to be involved in hypermutation during immunoglobulin class switch recombination. Mutations in this gene result in XPV, a variant type of xeroderma pigmentosum. Several transcript variants encoding different isoforms have been found for this gene.

• Description :

  This is a POLH Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  DNA polymerase eta, FLJ16395, FLJ21978, Polh, POLH, polymerase DNA directed eta, RAD30, RAD30 homolog A, RAD30A, Xeroderma pigmentosum variant type protein, XP V, XPV

• Swiss Prot :

  Q9Y253

• Accession Number :

  BC015742

• Reactivity :

  Human, Mouse

• Immunogen :

  Fusion protein of human POLH

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  IHC, ELISA

• Purification Method :

  Antigen affinity purification

• Assay Type :

  Antibody

• Concentration :

  1.08 mg/mL

• Dilution :

  IHC 1:50-1:300, ELISA 1:5000-1:10000

• Buffer :

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source :

  Rabbit

• Isotype :

  IgG