ISCU Polyclonal Antibody

• Background:

  This gene encodes a component of the iron-sulfur (Fe-S) cluster scaffold. Fe-S clusters are cofactors that play a role in the function of a diverse set of enzymes, including those that regulate metabolism, iron homeostasis, and oxidative stress response. Alternative splicing results in transcript variants encoding different protein isoforms that localize either to the cytosol or to the mitochondrion. Mutations in this gene have been found in patients with hereditary myopathy with lactic acidosis. A disease-associated mutation in an intron may activate a cryptic splice site, resulting in the production of a splice variant encoding a putatively non-functional protein. A pseudogene of this gene is present on chromosome 1.

• Description:

  This is a ISCU Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  2310020H20Rik, HML, hnifU, Iron sulfur cluster assembly enzyme ISCU mitochondrial, Iron sulfur cluster scaffold homolog (E. coli), Iron sulfur cluster scaffold homolog, Iron-sulfur cluster assembly enzyme ISCU, Iscu, IscU iron sulfur cluster scaffold homolog, ISCU

• Swiss Prot:

  Q9H1K1

• Accession Number:

  BC011906

• Reactivity:

  Human, Mouse

• Immunogen:

  Fusion protein of human ISCU

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, ELISA

• Purification Method:

  Antigen affinity purification

• Assay Type:

  Antibody

• Concentration:

  0.96 mg/mL

• Dilution:

  WB 1:500-1:2000, ELISA 1:5000-1:10000

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  18 kDa

• Observed Molecular Weight:

  Refer to figures

• Host or Source:

  Rabbit

• Isotype:

  IgG