TP63 Polyclonal Antibody

CAT: 0866-RD218722A-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:0866-RD218722A-01Size:20 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
TP63, also named KET, P63, P73H, P73L and TP73L, belongs to the p53 family. It is a homologue of the tumor suppressor p53 and p73 genes. It is involved in malignancy acquisition and maintenance of cells. Unlike p53, the p63 gene encodes multiple isotypes with remarkably divergent abilities to transactivate p53 reporter genes and induce apoptosis. TP63 acts as a sequence specific DNA binding transcriptional activator or repressor. TP63 has 12 isoforms with MW 40kd (P40),50kd (P60),63kd (P63) and 73kd (P73L) . It is Nuclear stain.
Description
This is a TP63 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
AIS, Amplified in squamous cell carcinoma, B (p51A), B (p51B), Chronic ulcerative stomatitis protein, CUSP, DN p63 alpha 1, DNp63, EEC3, id:ibd3516, Keratinocyte transcription factor, Keratinocyte transcription factor KET, KET, LMS, MGC115972, MGC192897, NBP, OFC8, OTTHUMP00
Swiss Prot
Q9H3D4
Accession Number
NP001316074
Reactivity
Human, Mouse, Rat
Immunogen
Fusion protein of human TP63
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
1.14 mg/mL
Dilution
IHC 1:50-1:200, ELISA 1:5000-1:10000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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