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CHRD Polyclonal Antibody

CAT: 866-RD218617A-01Size: 20 µLDry Ice: NoHazardous: No
20 µLSelected
PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CHRD (Chordin) is a Protein Coding gene. Diseases associated with CHRD include Cornelia De Lange Syndrome. Among its related pathways are Mesodermal Commitment Pathway and TGF-beta signaling pathway (KEGG) . GO annotations related to this gene include heparin binding and syndecan binding. An important paralog of this gene is CHRDL2.This gene encodes a secreted protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta-like bone morphogenetic proteins and sequestering them in latent complexes. The encoded protein may also have roles in organogenesis and during adulthood. It has been suggested that this gene could be a candidate gene for Cornelia de Lange syndrome. Reduced expression of this gene results in enhanced bone regeneration. Alternative splicing results in multiple transcript variants. Other alternative splice variants have been described but their full length sequence has not been determined.
Description
This is a CHRD Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
Chordin, chrd, CHRD, MGC133038, Shortgastrulation protein, SOG
Swiss Prot
Q9H2X0
Accession Number
BC112345
Reactivity
Human, Mouse, Rat
Immunogen
Fusion protein of human CHRD
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
0.8 mg/mL
Dilution
IHC 1:30-1:150, ELISA 1:5000-1:10000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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