CD86 Polyclonal Antibody

• Background :

  This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.

• Description :

  This is a CD86 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  Activation B7-2 antigen 3, Activation B7-2 antigen, B-lymphocyte activation antigen B7-2 2, B-lymphocyte activation antigen B7-2, B7 2, B7, B7-2, B7.2, B70, B72 antigen, BU63, CD28 antigen ligand 2 2, CD28 antigen ligand 2, Cd28l2, CD28LG2, CD86, CD86 antigen, CD86 antige

• Swiss Prot :

  P42081

• Accession Number :

  BC040261

• Reactivity :

  Human

• Immunogen :

  Fusion protein of human CD86

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  WB, IHC, ELISA

• Purification Method :

  Antigen affinity purification

• Assay Type :

  Antibody

• Concentration :

  0.5 mg/mL

• Dilution :

  WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000

• Buffer :

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  38 kDa

• Observed Molecular Weight :

  Refer to figures

• Host or Source :

  Rabbit

• Isotype :

  IgG