ATF6B Polyclonal Antibody

CAT: 0866-RD218330A-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:0866-RD218330A-01Size:20 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum; however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for this gene.
Description
This is a ATF6B Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
ATF6B, CREBL1, G13, Cyclic AMP-dependent transcription factor ATF-6 beta, cAMP-dependent transcription factor ATF-6 beta, Activating transcription factor 6 beta, ATF6-beta, Protein G13, cAMP response element-binding protein-related protein
Swiss Prot
Q99941
Accession Number
BC008394
Reactivity
Human, Mouse
Immunogen
Fusion protein of human ATF6B
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, ELISA
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
0.5 mg/mL
Dilution
WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
77 kDa
Observed Molecular Weight
Refer to figures
Host or Source
Rabbit
Isotype
IgG

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