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CAPN6 Polyclonal Antibody

CAT: 0866-RD218214A-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:0866-RD218214A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is highly expressed in the placenta. Its C-terminal region lacks any homology to the calmodulin-like domain of other calpains. The protein lacks critical active site residues and thus is suggested to be proteolytically inactive. The protein may play a role in tumor formation by inhibiting apoptosis and promoting angiogenesis.
Description
This is a CAPN6 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
CALP M, Calpain-6, Calpain-like protease X-linked, Calpamodulin, CalpM, CAN6, CANP X, CANPX, CAPN 6, Capn6
Swiss Prot
Q9Y6Q1
Accession Number
BC000730
Reactivity
Human, Mouse, Rat
Immunogen
Fusion protein of human CAPN6
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, ELISA
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
0.78 mg/mL
Dilution
WB 1:500-1:2000, ELISA 1:5000-1:10000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
75 kDa
Observed Molecular Weight
Refer to figures
Host or Source
Rabbit
Isotype
IgG

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