LDHA Polyclonal Antibody

• Background:

  LDHA, also named as LDH-M and NY-REN-59, is an enzyme which catalyzes the inter-conversion of pyruvate and L-lactate with concomitant inter-conversion of NADH and NAD+. LDHA is found in most somatic tissues, though predominantly in muscle tissue and tumours, and belongs to the lactate dehydrogenase family. It has long been known that many human cancers have higher LDHA levels compared to normal tissues. It has also been shown that LDHA plays an important role in the development, invasion and metastasis of malignancies. Mutations in LDHA have been linked to exertional myoglobinuria. LDHA has some isoforms with MW 26-40 kDa.

• Description:

  This is a LDHA Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  Cell proliferation-inducing gene 19 protein, L lactate dehydrogenase A chain, Lactate dehydrogenase A, LDH A, LDH M, LDH muscle subunit, LDH1, LDH5, LDHA, PIG 19, PIG19, Renal carcinoma antigen NY-REN-59

• Swiss Prot:

  P00338

• Accession Number:

  NP005557

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Synthetic peptide of human LDHA

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IHC, ELISA

• Purification Method:

  Antigen affinity purification

• Assay Type:

  Antibody

• Concentration:

  0.72 mg/mL

• Dilution:

  WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  37 kDa

• Observed Molecular Weight:

  Refer to figures

• Host or Source:

  Rabbit

• Isotype:

  IgG