FLNC Polyclonal Antibody

• Background:

  This gene encodes one of three related filamin genes, specifically gamma filamin. These filamin proteins crosslink actin filaments into orthogonal networks in cortical cytoplasm and participate in the anchoring of membrane proteins for the actin cytoskeleton. Three functional domains exist in filamin: an N-terminal filamentous actin-binding domain, a C-terminal self-association domain, and a membrane glycoprotein-binding domain. Two transcript variants encoding different isoforms have been found for this gene.

• Description:

  This is a FLNC Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  ABPL, Actin binding like protein, FIlamin 2, Filamin C, FLN2, Gamma filamin

• Swiss Prot:

  Q14315

• Accession Number:

  NP001449

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Synthetic peptide of human FLNC

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IHC, ELISA

• Purification Method:

  Antigen affinity purification

• Assay Type:

  Antibody

• Concentration:

  0.9 mg/mL

• Dilution:

  WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  291 kDa

• Observed Molecular Weight:

  Refer to figures

• Host or Source:

  Rabbit

• Isotype:

  IgG